Exercise may protect brain health by lowering cardiovascular risk factors

A new study investigates the mechanisms involved in the relationship between exercise and brain health.
Previous research had shown that larger gray matter volume can help protect against dementia by improving brain function.
The new study shows that insulin resistance and BMI mediate the relationship between larger and smaller brain gray matter volumes (the part of the brain involved in processing information).
The research is published in the April 2022 online issue of Neurology, the medical journal of the American Academy of Neurology.

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